Research Interests

Host-Pathogen Interactions:


The area of current research is 'Chemical & Molecular Cell Biology of host-pathogen interactions'. The research direction involves understanding genetic, biochemical & metabolic basis underlying the strategies used by fungal pathogens to evade host immunity, and the mechanisms by which plant/animal hosts respond to defend themselves against the microbial attack.
 


Plant-Fungus Interactions:


The major focus is to study the chemical language used by these fungal pathogens, using innovative cell-based assays, in conjunction with the functional genomics and analytical chemistry tools, to understand the molecular mechanisms at the interface. We use the model patho-system of Rice-Blast disease caused by Magnaporthe oryzae for the plant-fungus interaction studies.


Fungus-Fungus Interactions:


We are using Candida glabrata & C. albicans for the studies on the opportunistic fungal pathogens of animal host. The broad research interest is to understand the kind of relationship the usually co-isolated two fungal commensals establish through their interactions with each other while living in the host, especially during pathogenesis.

Host-Microbe Interaction Lab
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